Seroatlas · Human Serome Atlas

OR1D4

Olfactory receptor 1D4

Also known as: OR1D4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P47884
Gene: OR1D4
Canonical length: 311 aa

OverviewNCBI Gene

No narrative summary is available for OR1D4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

311 residues, UniProt reviewed canonical sequence.

>P47884|OR1D4
     1  MDGDNQSENS QFLLLGISES PEQQQILFWM FLSMYLVTVL GNVLIILAIS SDSHLHTPMY
    61  FFLANLSFTD LFFVTNTIPK MLVNFQSQNK AISYAGCLTQ LYFLVSLVTL DNLILAVMAY
   121  DRYVAICCPL HYVTAMSPGL CVLLLSLCWG LSVLYGLLLT FLLTRVTFCG PREIHYLFCD
   181  MYILLWLACS NTHIIHTALI ATGCFIFLTL LGFMTTSYVR IVRTILQMPS ASKKYKTFST
   241  CASHLGVVSL FYGTLAMVYL QPLHTYSMKD SVATVMYAVL TPMMNPFIYS LRNKDMHGAP
   301  GRVLWRPFQR P

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR1D4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.29

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR1D4 as an antibody target. Whether an autoantibody or antibody against OR1D4 could matter depends on whether native OR1D4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR1D4 is annotated at the cell surface, where native OR1D4 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR1D4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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