Seroatlas · Human Serome Atlas

OR14L1

Olfactory receptor 14L1

Also known as: O14L1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NHC6
Gene: OR14L1
Canonical length: 325 aa

OverviewNCBI Gene

No narrative summary is available for OR14L1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

325 residues, UniProt reviewed canonical sequence.

>Q8NHC6|OR14L1
     1  MAQFNKNQLI ACRRNGTTTS DFNQTEVAEF FLMGFSNSWD IQIVHAALFF LVYLAAVIGN
    61  LLIIILTTLD VHLQTPMYFF LRNLSFLDFC YISVTIPKSI VSSLTHDTSI SFFGCALQAF
   121  FFMDLATTEV AILTVMSYDR YMAICRPLHY EVIINQGVCL RMMAMSWLSG VICGFMHVIA
   181  TFSLPFCGRN RIRQFFCNIP QLLSLLDPKV ITIEIGVMVF GTSLVIISFV VITLSYMYIF
   241  SVIMRIPSKE GRSKTFSTCI PHLVVVTLFM ISGSIAYVKP ISNSPPVLDV FLSAFYTVVP
   301  PTLNPVIYSL RNRDMKAALR RQCGP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR14L1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 7
Mean surface accessibility (rSASA): 0.28

OntologyGO

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR14L1 as an antibody target. Whether an autoantibody or antibody against OR14L1 could matter depends on whether native OR14L1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR14L1 is annotated at the cell surface, where native OR14L1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR14L1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...