Seroatlas · Human Serome Atlas

OR12D1

Olfactory receptor 12D1

Also known as: O12D1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0DN82
Gene
OR12D1
Canonical length
320 aa
Protein class
Predicted membrane proteins

OverviewNCBI Gene

No narrative summary is available for OR12D1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

320 residues, UniProt reviewed canonical sequence.

>P0DN82|OR12D1
     1  MLNTTSVTEF LLLGVTDIQE LQPFLFVVFL TIYFISVAGN GAILMIVISD PRLHSPMYFF
    61  LGNLSCLDIC YSSVTLPKML QNFLSAHKAI SFLGCISQLH FFHFLGSTEA MLLAVMAFDR
   121  FVAICKPLRY TVIMNPQLCT QMAITIWMIG FFHALLHSLM TSRLNFCGSN RIYHFFCDVK
   181  PLLKLACGNT ELNQWLLSTV TGTIAMGPFF LTLLSYFYII THLFFKTHSF SMLRKALSTC
   241  ASHFMVVILL YAPVLFTYIH HASGTSMDQD RITAIMYTVV TPVLNPLIYT LRNKEVKGAF
   301  NRAMKRWLWP KEILKNSSEA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against OR12D1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Cell surface
Secreted
No
Transmembrane segments
7
Mean surface accessibility (rSASA)
0.28
Highest tissue expression
0 nTPM

Expression across tissuesHPA

Tissue

  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM
  • cerebral cortex: 0 nTPM

Single-cell type

  • ependymal cells: 17 nCPM
  • brain excitatory neurons: 0.2 nCPM
  • brain inhibitory neurons: 0.1 nCPM
  • adipocytes: 0 nCPM
  • adrenal cortex cells: 0 nCPM
  • adrenal medulla cells: 0 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • medulla oblongata: 1 nTPM
  • spinal cord: 0.5 nTPM
  • midbrain: 0.3 nTPM
  • pons: 0.2 nTPM
  • hippocampal formation: 0.1 nTPM
  • hypothalamus: 0.1 nTPM

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads OR12D1 as an antibody target. Whether an autoantibody or antibody against OR12D1 could matter depends on whether native OR12D1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

OR12D1 is annotated at the cell surface, where native OR12D1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label OR12D1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/OR12D1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

© 2026 · Seroatlas, Discover Oregon LLC · Terms of use

Loading the interactive Seroatlas protein explorer...