Seroatlas · Human Serome Atlas

NECTIN3-AS1

Uncharacterized protein NECTIN3-AS1

Also known as: N3AS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q1RN00
Gene
NECTIN3-AS1
Canonical length
199 aa

OverviewNCBI Gene

No narrative summary is available for NECTIN3-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

199 residues, UniProt reviewed canonical sequence.

>Q1RN00|NECTIN3-AS1
     1  MLPVQRRKLD PLLKKYRHHK KATRTKRRRK EKMEAQCSPV PPTPSTPPQS EEDEAVDKKP
    61  TLLSAQEDTP DLLHEDRLQY LQEEGSGVMH QECQIQSCEL SVAQKPRPSS PAVTSLASPP
   121  LCFGSFLSCV CQTFSRSRKQ KPPRRKGNNQ AEAGGDAEVL RPGPAKPELS LSKTCSHLKL
   181  IELSFVFSFI VLSVCHCSS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NECTIN3-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.69

Protein domainsUniProt · Pfam · InterPro

  • Protein of unknown function DUF4672
  • Domain of unknown function (DUF4672)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NECTIN3-AS1 as an antibody target. Whether an autoantibody or antibody against NECTIN3-AS1 could matter depends on whether native NECTIN3-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NECTIN3-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NECTIN3-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/NECTIN3-AS1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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