Seroatlas · Human Serome Atlas

NDUFV1-DT

Uncharacterized protein NDUFV1-DT

Also known as: CK072_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NBR9
Gene: NDUFV1-DT
Canonical length: 251 aa

OverviewNCBI Gene

No narrative summary is available for NDUFV1-DT in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

251 residues, UniProt reviewed canonical sequence.

>Q8NBR9|NDUFV1-DT
     1  MTQLPELGLR SPNNKSPTGP HPLEHLLARL LKRRRRSTLM SSPRSLLCSI SGPGSHLLST
    61  HPILCHSVYQ PPQPASRPQA KRYQGLLPVP LAPHPLCLSG QLYLPNIPCT VIDGCGPVIS
   121  HLKLTMYPWG LPPSHLGSSS PFSANMEQWD YYKSQTRFAP FLPESFCGSP LPSEQSSRPF
   181  GLAFKVLCAA TCQPPQFQLL WLCPYKLDLH QRICLPPNLA LVLLGALWTS PPPGSFLQPP
   241  YNRPYKLYKT N

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NDUFV1-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.64

DiseaseUniProt · ClinVar · IEDB · PubMed

Four sources answering four different questions about NDUFV1-DT.

Disease | ImmuneIEDB

Conditions an epitope on NDUFV1-DT was assayed in.

melanoma T cell

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NDUFV1-DT as an antibody target. Whether an autoantibody or antibody against NDUFV1-DT could matter depends on whether native NDUFV1-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NDUFV1-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NDUFV1-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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