Seroatlas · Human Serome Atlas

NAP1L6P

Putative nucleosome assembly protein 1-like 6

Also known as: NP1L6_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NFF2
Gene: NAP1L6P
Canonical length: 107 aa

OverviewNCBI Gene

No narrative summary is available for NAP1L6P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

107 residues, UniProt reviewed canonical sequence.

>A6NFF2|NAP1L6P
     1  MMEGLGEHST AGEMGPLLGA VAATASPQSL MEYSSDADFI ESLPLVVKYR VYTLKKLQAK
    61  CAVLEAKYLR EFHSVERKFA TIYGPLLEKR RQITNALYEP TKEECER

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NAP1L6P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.56

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

nucleosome assembly

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NAP1L6P as an antibody target. Whether an autoantibody or antibody against NAP1L6P could matter depends on whether native NAP1L6P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NAP1L6P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NAP1L6P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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