Seroatlas · Human Serome Atlas

MYCLP1

Putative myc-like protein MYCLP1

Also known as: MYCP1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P12525
Gene: MYCLP1
Canonical length: 358 aa

OverviewNCBI Gene

No narrative summary is available for MYCLP1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

358 residues, UniProt reviewed canonical sequence.

>P12525|MYCLP1
     1  MDRDSYHHYF YDYDGGEDFY RSTTPSEDIW KKFELVPPPW DLGPAAGNPA LSFGLLEPWP
    61  VGCAGDETES QDYWKAWDAN YASLIRRDCM WSGFSTQEPL ERAVSDLLAV GAPSGYSPKE
   121  FATPDYTPEL EAGNLAPIFP CLLGEPKIQA CSRSESPSDS EGEEIDVTVK KRQSLSTRKP
   181  VIIAVRADLL DPRMNLFHIS IHQQQHNYAA PFPPESCFQE GAPKRMPPKE ALEREAPGGK
   241  DDKEDEEIVS LPPVESEAAQ SCQPKPIHYD TENWTKKKYH SYLERKRRND QRSRFLALRD
   301  EVPALASCSR VSKVMILVKA TEYLHELAEA EERMATEKRQ LECQRRQLQK RIEYLSSY

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MYCLP1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

OntologyGO

Biological processes

regulation of transcription by RNA polymerase II

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MYCLP1 as an antibody target. Whether an autoantibody or antibody against MYCLP1 could matter depends on whether native MYCLP1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MYCLP1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MYCLP1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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