Seroatlas · Human Serome Atlas

MPTX1

Putative mucosal pentraxin homolog

Also known as: MPTX_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MV57
Gene: MPTX1
Canonical length: 137 aa

OverviewNCBI Gene

No narrative summary is available for MPTX1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

137 residues, UniProt reviewed canonical sequence.

>A8MV57|MPTX1
     1  MGMYLLHIGN AAVTFNGPTP CPRSPYASTH VNVSWESASG IATLWANGKL VGRKGVWKGY
    61  SVGEEAKIIL GQEQDSFGGH FDENQSFVGV IWDVFLWDHV LPPKEMCDSC YSGSLLNRHT
   121  LTYEDNGYVV TKPKVWA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MPTX1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

OntologyGO

Molecular functions

metal ion binding

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MPTX1 as an antibody target. Whether an autoantibody or antibody against MPTX1 could matter depends on whether native MPTX1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MPTX1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MPTX1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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