Seroatlas · Human Serome Atlas

MMP24OS

Protein MMP24OS

Also known as: MMP24-AS1, MMPOS_HUMAN

Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A0A0U1RRL7
Gene
MMP24OS
Ensembl
ENSG00000126005
Chromosome
20
Canonical length
71 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

No narrative summary is available for MMP24OS in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

71 residues, UniProt reviewed canonical sequence.

>A0A0U1RRL7|MMP24OS
     1  MGAQLSGGRG APEPAQTQPQ PQPQPAAPEG PEQPRHPPQP QPQPQPQPQP EPSPWGPLDD
    61  VRFLIACTSW Y

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MMP24OS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.7
Highest tissue expression
83 nTPM

Expression across tissuesHPA

Tissue

  • kidney: 83 nTPM
  • choroid plexus: 78 nTPM
  • pituitary gland: 68 nTPM
  • adrenal gland: 62 nTPM
  • amygdala: 55 nTPM
  • esophagus: 54 nTPM

Single-cell type

  • neutrophils: 110 nCPM
  • microglia: 89 nCPM
  • fibro-adipogenic progenitors: 85 nCPM
  • epicardial cells: 75 nCPM
  • thymocytes: 69 nCPM
  • podocytes: 68 nCPM

Immune cell

  • eosinophil: 7.5 nTPM
  • neutrophil: 6.7 nTPM
  • non-classical monocyte: 5.5 nTPM
  • intermediate monocyte: 3.2 nTPM
  • basophil: 3 nTPM
  • naive B-cell: 2.4 nTPM

Brain region

  • choroid plexus: 122 nTPM
  • cerebral cortex: 115 nTPM
  • thalamus: 105 nTPM
  • medulla oblongata: 100 nTPM
  • pons: 100 nTPM
  • amygdala: 99 nTPM

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MMP24OS as an antibody target. Whether an autoantibody or antibody against MMP24OS could matter depends on whether native MMP24OS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MMP24OS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MMP24OS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/MMP24OS. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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