MMP24OS
Protein MMP24OS
Also known as: MMP24-AS1, MMPOS_HUMAN
Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene
Protein identityUniProt · HPA
- UniProt accession
- A0A0U1RRL7
- Gene
- MMP24OS
- Ensembl
- ENSG00000126005
- Chromosome
- 20
- Canonical length
- 71 aa
- Protein class
- Predicted intracellular proteins
OverviewNCBI Gene
No narrative summary is available for MMP24OS in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
71 residues, UniProt reviewed canonical sequence.
>A0A0U1RRL7|MMP24OS
1 MGAQLSGGRG APEPAQTQPQ PQPQPAAPEG PEQPRHPPQP QPQPQPQPQP EPSPWGPLDD
61 VRFLIACTSW YLocalizationUniProt · AlphaFold · HPA
Whether an antibody against MMP24OS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.7
- Highest tissue expression
- 83 nTPM
Expression across tissuesHPA
Tissue
- kidney: 83 nTPM
- choroid plexus: 78 nTPM
- pituitary gland: 68 nTPM
- adrenal gland: 62 nTPM
- amygdala: 55 nTPM
- esophagus: 54 nTPM
Single-cell type
- neutrophils: 110 nCPM
- microglia: 89 nCPM
- fibro-adipogenic progenitors: 85 nCPM
- epicardial cells: 75 nCPM
- thymocytes: 69 nCPM
- podocytes: 68 nCPM
Immune cell
- eosinophil: 7.5 nTPM
- neutrophil: 6.7 nTPM
- non-classical monocyte: 5.5 nTPM
- intermediate monocyte: 3.2 nTPM
- basophil: 3 nTPM
- naive B-cell: 2.4 nTPM
Brain region
- choroid plexus: 122 nTPM
- cerebral cortex: 115 nTPM
- thalamus: 105 nTPM
- medulla oblongata: 100 nTPM
- pons: 100 nTPM
- amygdala: 99 nTPM
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads MMP24OS as an antibody target. Whether an autoantibody or antibody against MMP24OS could matter depends on whether native MMP24OS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
MMP24OS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label MMP24OS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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