Seroatlas · Human Serome Atlas

MIR9-1HG

Protein CROC-4

Also known as: CROC4_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q13536
Gene: MIR9-1HG
Canonical length: 156 aa

OverviewNCBI Gene

No narrative summary is available for MIR9-1HG in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

156 residues, UniProt reviewed canonical sequence.

>Q13536|MIR9-1HG
     1  MFLTEDLITF NLRNFLLFQL WESSFSPGAG GFCTTLPPSF LRVDDRATSS TTDSSRAPSS
    61  PRPPGSTSHC GISTRCTERC LCVLPLRTSQ VPDVMAPQHD QEKFHDLAYS CLGKSFSMSN
   121  QDLYGYSTSS LALGLAWLSW ETKKKNVLHL VGLDSL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MIR9-1HG can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.62

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

positive regulation of transcription by RNA polymerase II

Cellular components

nucleus

KeywordsUniProt

Nucleus

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MIR9-1HG as an antibody target. Whether an autoantibody or antibody against MIR9-1HG could matter depends on whether native MIR9-1HG is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MIR9-1HG is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MIR9-1HG as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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