Seroatlas · Human Serome Atlas

METTL15P1

Putative methyltransferase-like protein 15P1

Also known as: ME15P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C7V9
Gene: METTL15P1
Canonical length: 234 aa

OverviewNCBI Gene

No narrative summary is available for METTL15P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

234 residues, UniProt reviewed canonical sequence.

>P0C7V9|METTL15P1
     1  MLRYPYFCRM YKECLSCWLE SGIPNLGVWP KRIHTTAEKY REYEAREQTD QTQVQELHRS
    61  QDRDFETMAK LHIPVMVDEV VHCLSPQKGQ IFLDMTFGSG GHTKAILQKE SDIVLYALDR
   121  DPTAYALAEH LSELYPKQIR AMLGQFSQAE ALLMKAGVQP GTFDGVLMDL GCSSMQLDTP
   181  ERGSSLRKDG PLDIRMDGGR NISSLCYLYT ERLTTAIYLY CHQDFPGSSH ICEQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against METTL15P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.43

OntologyGO

Biological processes

rRNA base methylation

Molecular functions

rRNA (cytosine-N4-)-methyltransferase activity

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads METTL15P1 as an antibody target. Whether an autoantibody or antibody against METTL15P1 could matter depends on whether native METTL15P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

METTL15P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label METTL15P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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