Seroatlas · Human Serome Atlas

MED14OS

Putative uncharacterized protein MED14OS

Also known as: M14OS_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0DP75
Gene: MED14OS
Canonical length: 135 aa

OverviewNCBI Gene

No narrative summary is available for MED14OS in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

135 residues, UniProt reviewed canonical sequence.

>P0DP75|MED14OS
     1  MRSSSLPGAR SPRRNGSGQS RHRLPPGRLR TGSRAPTAEA RPHVARSPPT PGTGARGGGR
    61  RGWGGSRAAP QRGSCASANA QKQLRQTAAT YMLTARGGSR SAERKGDLQR TFRQVGQTMP
   121  MVPPLDFTMN AASVE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MED14OS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MED14OS as an antibody target. Whether an autoantibody or antibody against MED14OS could matter depends on whether native MED14OS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MED14OS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MED14OS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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