Seroatlas · Human Serome Atlas

LRRC37A5P

Putative protein LRRC37A5P

Also known as: L37A5_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q49AS3
Gene
LRRC37A5P
Canonical length
106 aa

OverviewNCBI Gene

No narrative summary is available for LRRC37A5P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

106 residues, UniProt reviewed canonical sequence.

>Q49AS3|LRRC37A5P
     1  MNRNILEEML QYLLIDWIVG DQFEIQLNQQ LWSLIPNNDV RRLVSHVIRT LKTDCTETHL
    61  QLACAKLISR TGLLMKLLSE QQELRTVSMT AWKPRMNRKS RSRMRS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LRRC37A5P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.48

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LRRC37A5P as an antibody target. Whether an autoantibody or antibody against LRRC37A5P could matter depends on whether native LRRC37A5P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LRRC37A5P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LRRC37A5P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/LRRC37A5P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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