Seroatlas · Human Serome Atlas

LINC03122

Uncharacterized protein encoded by LINC03122

Also known as: CE064_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q2M2E5
Gene: LINC03122
Canonical length: 130 aa

OverviewNCBI Gene

No narrative summary is available for LINC03122 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

130 residues, UniProt reviewed canonical sequence.

>Q2M2E5|LINC03122
     1  MLAPLFLCCL RNLFRKLISF QPPQLGRTNM HYSKLPRTAI ETEFKQNVGP PPKDLTAEVY
    61  FPSIKSRSHL PAVFYNQYFK HPKCVGEYGP KNGAERQIEE RKVLPTTMMF SMLADCVLKS
   121  TPIPILGVAM

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC03122 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.65

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC03122 as an antibody target. Whether an autoantibody or antibody against LINC03122 could matter depends on whether native LINC03122 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC03122 is annotated as secreted, so native LINC03122 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label LINC03122 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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