Seroatlas · Human Serome Atlas

LINC03042

Uncharacterized protein LINC03042

Also known as: CH086_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZUL3
Gene: LINC03042
Canonical length: 223 aa

OverviewNCBI Gene

No narrative summary is available for LINC03042 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

223 residues, UniProt reviewed canonical sequence.

>Q6ZUL3|LINC03042
     1  MRPLGKGLLP AEELIRSNLG VGRSLRDCLS QSGKLAEELG SKRLKPAKFG TEGKERVEQR
    61  TERQRTGSSK EPRMQIICRR RWREPPPRLL WGCLMPRAQP LLHVTAYENT GHWERLASVV
   121  SSKTQQPTVI SHSSISITFS HYPPATLDSF LVLEPIKLFP VSSLRSPLCL NCGSCRESIR
   181  ISGELIGNAH SPAPPRTPEL ETLGWDKQAV LSGAQVILVC AEV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC03042 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.47

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

Protein of unknown function DUF5553
Family of unknown function (DUF5553)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC03042 as an antibody target. Whether an autoantibody or antibody against LINC03042 could matter depends on whether native LINC03042 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC03042 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC03042 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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