Seroatlas · Human Serome Atlas

LINC02914

Testis-specific protein LINC02914

Also known as: CN177_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q52M58
Gene: LINC02914
Canonical length: 125 aa

OverviewNCBI Gene

No narrative summary is available for LINC02914 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

125 residues, UniProt reviewed canonical sequence.

>Q52M58|LINC02914
     1  MHRKEPGARL EATRGAARPH KQGTKPMITR PSVSQLGEGK CPSSQHLQSL RHNKQHALTL
    61  TKARCCGECS TCFCTEEKSE CQRHEETSPG SCNHQIMSAS TISAFCATPR FKQLFKGTVE
   121  QMSQM

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC02914 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.66

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 2% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Cellular components

Protein domainsUniProt · Pfam · InterPro

Testis-specific protein LINC02914-like
Family of unknown function (DUF5544)

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC02914 as an antibody target. Whether an autoantibody or antibody against LINC02914 could matter depends on whether native LINC02914 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC02914 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC02914 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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