Seroatlas · Human Serome Atlas

LINC02881

Uncharacterized protein encoded by LINC02881

Also known as: CJ142_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
B7Z368
Gene
LINC02881
Canonical length
130 aa

OverviewNCBI Gene

No narrative summary is available for LINC02881 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

130 residues, UniProt reviewed canonical sequence.

>B7Z368|LINC02881
     1  MRMYSSDAHE RPPSPSLGTT PPHPLPPTGS PRPRQDSAAG NSEEREPRGL RRASGVGSSC
    61  KRPTVCMGRQ QGLPFCTVCG YRCSSPERTR GRCAVGKVRV AGGGGAPGGG AGMRCCGCRE
   121  RNINKELELF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC02881 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.69

Protein domainsUniProt · Pfam · InterPro

  • Protein of of unknown function DUF5558
  • Family of unknown function (DUF5558)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC02881 as an antibody target. Whether an autoantibody or antibody against LINC02881 could matter depends on whether native LINC02881 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC02881 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC02881 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/LINC02881. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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