Seroatlas · Human Serome Atlas

LINC02875

Putative uncharacterized protein LINC02875

Also known as: CQ082_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q86X59
Gene: LINC02875
Canonical length: 251 aa

OverviewNCBI Gene

No narrative summary is available for LINC02875 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

251 residues, UniProt reviewed canonical sequence.

>Q86X59|LINC02875
     1  MGRPLEGQPL RALDLYPEPA FLRSGKDPKS SPASSPSFAV LGPEVRSTGG QAGSRRRPSA
    61  PCSQDRAAAE GAPALLGGSP SSGSPGHPPG SAFGVEAGCR ALNVSEHARG GFALGLPFGL
   121  SGGAYLFLLL DGAGDPKPTP EAPISSADGR AWFPSESSWQ LPQLPAGSTS GSEPRARPGL
   181  GPRQLLTGPR DGAAGQGPGR GLTARLGRER EIDCGPRQAG HGGTATDTGR AGSGARHRPP
   241  RDRGTPGLRT H

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC02875 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.75

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC02875 as an antibody target. Whether an autoantibody or antibody against LINC02875 could matter depends on whether native LINC02875 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC02875 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC02875 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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