Seroatlas · Human Serome Atlas

LINC02694

Putative uncharacterized protein encoded by LINC02694

Also known as: CO053_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8NAA6
Gene
LINC02694
Canonical length
179 aa

OverviewNCBI Gene

No narrative summary is available for LINC02694 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

179 residues, UniProt reviewed canonical sequence.

>Q8NAA6|LINC02694
     1  MELQGAQEDL GISLSSPRRN HETRPGSKAK GRSSICLQAS VWMAGGKLRL RASEHLTQGH
    61  QQELRDWNLG EDASLLFSKS PFGAGKLIQA PAHVFRQCWV QGNAWISCIT KFDSKRSPEV
   121  ASSPSYLTVP RRSPLPVFLR PSDRCVCGGC YLGKSTRRRA CQSLLSDPLG VTFPTQTRP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC02694 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.65

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

  • Protein of unknown function DUF5556
  • Family of unknown function (DUF5556)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC02694 as an antibody target. Whether an autoantibody or antibody against LINC02694 could matter depends on whether native LINC02694 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC02694 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC02694 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/LINC02694. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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