Seroatlas · Human Serome Atlas

LINC02693

Putative uncharacterized protein LINC02693

Also known as: CQ051_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MQB3
Gene: LINC02693
Canonical length: 221 aa

OverviewNCBI Gene

No narrative summary is available for LINC02693 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

221 residues, UniProt reviewed canonical sequence.

>A8MQB3|LINC02693
     1  MGEKSRRKGP APRHADGKLG RTCDHPYAPW SFTPSSRAPT AWVRPPCPVW ASRLQEHSPE
    61  PRRARAPPTR RAQAALYAPA LRLRDHLDRF SILMTSCTSW LQAPQAPGLC RDEQSSRISV
   121  PQLSGAPILL PDLEGTKLSN FQESSPLPHK HERKDKRSTP EEEGRSAPEK IIQSLKLCPG
   181  GHRPASLSSG CPAGCRLSFN LPPSMLLSVQ KCCMPSSLKT C

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC02693 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

Protein of unknown function DUF5545
Family of unknown function (DUF5545)

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC02693 as an antibody target. Whether an autoantibody or antibody against LINC02693 could matter depends on whether native LINC02693 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC02693 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC02693 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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