Seroatlas · Human Serome Atlas

LINC01599

Putative uncharacterized protein encoded by LINC01599

Also known as: CN183_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8WXQ3
Gene: LINC01599
Canonical length: 324 aa

OverviewNCBI Gene

No narrative summary is available for LINC01599 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

324 residues, UniProt reviewed canonical sequence.

>Q8WXQ3|LINC01599
     1  MEVLGFSNSK MDVRAKRQLE IWMEMAPSKP EPQGKAQQSQ PTSVLSAANA AQRGKCCCCR
    61  EGHSPEDYGR QWAENVENHP EVAAHTSCLQ SITPHFIAGE MGCTAKESQE QVPASITQIL
   121  RNPWFSRLDS PRSRCLHLAS SVDPIPGLQF FIVIVSDHQK VDREEEWKQG KIRKEIHWIP
   181  LFTMWSWLQC VEDRSIAGIP KLEHGDSHQT ESLLDVLVGG FWGVPHTAPP RLQEAGGPTG
   241  GCGVGGQPLG GRGQWVGEET GPVGGPHAWW VPPTAPGTSL VLLVLLAQPF QSSEWMPVSS
   301  HTPPGTQTNT AALLNVCTSY SEYV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC01599 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC01599 as an antibody target. Whether an autoantibody or antibody against LINC01599 could matter depends on whether native LINC01599 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC01599 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC01599 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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