Seroatlas · Human Serome Atlas

LINC01587

Uncharacterized protein encoded by LINC01587

Also known as: CD006_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q99440
Gene: LINC01587
Canonical length: 93 aa

OverviewNCBI Gene

No narrative summary is available for LINC01587 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

93 residues, UniProt reviewed canonical sequence.

>Q99440|LINC01587
     1  MDTQKQIHKT HNSKNQFFTI FFFLSVEFGK EGTRKNFYLL LSIGHYGRKS RRADLGTADT
    61  ADKTEPECFA ASWTFDPNPS VTVSGAHSTA VHQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC01587 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.53

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

nervous system development

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC01587 as an antibody target. Whether an autoantibody or antibody against LINC01587 could matter depends on whether native LINC01587 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC01587 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC01587 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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