Seroatlas · Human Serome Atlas

LINC01559

Putative uncharacterized protein encoded by LINC01559

Also known as: CL036_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q495D7
Gene: LINC01559
Canonical length: 138 aa

OverviewNCBI Gene

No narrative summary is available for LINC01559 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

138 residues, UniProt reviewed canonical sequence.

>Q495D7|LINC01559
     1  MERFLNSKAR RLGSCSHPAF YLLCVPDEDT SCSTIYLPLK RRADPDQLFS DLLGGTQRLW
    61  SNRFGNEESF PGRVRALVDT FCWIARAPPL GNPLRLEERI AWRIQRLKSG QTALIEKKKQ
   121  KIEEDVRHQC QQTTCDRC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC01559 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.47

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC01559 as an antibody target. Whether an autoantibody or antibody against LINC01559 could matter depends on whether native LINC01559 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC01559 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC01559 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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