Seroatlas · Human Serome Atlas

LINC01547

Uncharacterized protein encoded by LINC01547

Also known as: CU067_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P58512
Gene: LINC01547
Canonical length: 204 aa

OverviewNCBI Gene

No narrative summary is available for LINC01547 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

204 residues, UniProt reviewed canonical sequence.

>P58512|LINC01547
     1  MGWDCRRTTV ENPSPIRNCV NQEWPEGSSP GLTEGNTGLV RDLRPAHQDR SGTREDPAGQ
    61  ETTAITNPSP SLAADLAGDA LPGCLGAAAH QGPLLDRSSE STLGPQALEL EHCHERGCCR
   121  GCASFSPFPA PRCPSERLGA HSSRWAIRGR SKINPPPWAP ACLPGGFPAC LPAPKSSTDS
   181  ASSCFKGGRE FSDPLDIPGA GAMG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC01547 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.74

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Cellular components

endoplasmic reticulum

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC01547 as an antibody target. Whether an autoantibody or antibody against LINC01547 could matter depends on whether native LINC01547 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC01547 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC01547 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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