Seroatlas · Human Serome Atlas

LINC00869

Putative uncharacterized protein encoded by LINC00869

Also known as: F91A2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0C866
Gene
LINC00869
Canonical length
280 aa

OverviewNCBI Gene

No narrative summary is available for LINC00869 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

280 residues, UniProt reviewed canonical sequence.

>P0C866|LINC00869
     1  MLLSWGGGES RRPVQEASSA TDTDTNSQED PADTASVRSL SLSAGHTKHI AFLFDSTLTA
    61  FLMMGNLSPV QSTGEREAQR YFEHALTLRN TTLFLRHNKD LVVQTAQPDQ PNYGFPLDLL
   121  RCESLLGLDP ATGSRVLNKN YTLLVSMAPL TNEIRPVSSC TPQHIGPAIP EVSSVWFKQY
   181  IYVYHITGQG PPSLLLSKGT RPRKLPDIFQ SYDRLLITSW GHDPGVVPTS NVLTMLNDAL
   241  THSAVLIQEH GLHGIGETVH VPFPFDETEL QEDSCQYGCS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00869 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.4

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00869 as an antibody target. Whether an autoantibody or antibody against LINC00869 could matter depends on whether native LINC00869 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00869 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00869 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/LINC00869. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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