Seroatlas · Human Serome Atlas

LINC00862

Putative transmembrane protein encoded by LINC00862

Also known as: SIM16_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NCI5
Gene: LINC00862
Canonical length: 91 aa

OverviewNCBI Gene

No narrative summary is available for LINC00862 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

91 residues, UniProt reviewed canonical sequence.

>A6NCI5|LINC00862
     1  MVCYLYWETF PSISHLLKIT LSARDCHVCG LNLFIFMDPV ENQALHPVIM ALILMPSLHC
    61  FGNILILLFL KSPAQLFCRM SVDLALLFPH K

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00862 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.34

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00862 as an antibody target. Whether an autoantibody or antibody against LINC00862 could matter depends on whether native LINC00862 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00862 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00862 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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