Seroatlas · Human Serome Atlas

LINC00528

Putative uncharacterized protein encoded by LINC00528

Also known as: CV037_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q8N1L1
Gene
LINC00528
Canonical length
170 aa

OverviewNCBI Gene

No narrative summary is available for LINC00528 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

170 residues, UniProt reviewed canonical sequence.

>Q8N1L1|LINC00528
     1  MALLLSDWCP DGDADTHTGT DPGRTTHRLC ARERGVRGTQ PCPRIYLRLP AQNCEETRFC
    61  CASPGSVVLG HGAPRTASPP SALSHPSPLE GLSFSPFPPS VLSHPSPPEG LSFSLFHCLC
   121  SGKLSESPGC FWNSLGWSFS VLTEPGVWKV GEAIWVAENL AQPLTSPCAC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00528 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.6

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00528 as an antibody target. Whether an autoantibody or antibody against LINC00528 could matter depends on whether native LINC00528 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00528 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00528 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/LINC00528. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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