LINC00523
Putative uncharacterized protein encoded by LINC00523
Also known as: CN070_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for LINC00523 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
105 residues, UniProt reviewed canonical sequence.
>Q86TU6|LINC00523
1 MGIGTGHTSM NKGGKDVTLL ELSVEKRRWR INMETSKIIL EKMQSDDVLD GNRERSNERE
61 GRDSLSEKLK SKQNLKDEEK LRYIKTGKSI QVEGTVRAKA LRWVQLocalizationUniProt · AlphaFold · HPA
Whether an antibody against LINC00523 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.57
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 2% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads LINC00523 as an antibody target. Whether an autoantibody or antibody against LINC00523 could matter depends on whether native LINC00523 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
LINC00523 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label LINC00523 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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