Seroatlas · Human Serome Atlas

LINC00518

Putative uncharacterized protein encoded by LINC00518

Also known as: CF218_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N0U6
Gene: LINC00518
Canonical length: 118 aa

OverviewNCBI Gene

No narrative summary is available for LINC00518 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

118 residues, UniProt reviewed canonical sequence.

>Q8N0U6|LINC00518
     1  MDSSDETGSS FMSFWPHLQS DDLARNGITG FPYFSFIILN ESDQILELDG TLVKIWLLVP
    61  SHQPATHFKF EETKTHGPYV ITGDYPRSLW QKSASSLPAS PPCLWYFLPT LGCFCDHT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00518 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

DiseaseUniProt · ClinVar · IEDB · PubMed

Four sources answering four different questions about LINC00518.

Disease | ImmuneIEDB

Conditions an epitope on LINC00518 was assayed in.

melanoma T cell

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00518 as an antibody target. Whether an autoantibody or antibody against LINC00518 could matter depends on whether native LINC00518 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00518 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00518 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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