Seroatlas · Human Serome Atlas

LINC00482

Putative uncharacterized protein encoded by LINC00482

Also known as: CQ055_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N8I6
Gene: LINC00482
Canonical length: 264 aa

OverviewNCBI Gene

No narrative summary is available for LINC00482 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

264 residues, UniProt reviewed canonical sequence.

>Q8N8I6|LINC00482
     1  MPRSLKRAQL RSLLPRPPAV SHTQPWYRAA HPTTSPTAAS RDVHPASGAV PGPWLVEGTA
    61  VREGPQLQDA VPQRPTRPSK ALWPAQMSAA PAIRLGQMVP GDTRGLWGPQ GTLLTWTYRG
   121  GQGGRWTRRA EGPREGTFAE QRPHFQSSGA QQESRLAMGP PPLGLGDAAG DGRGQTGQEK
   181  GRAEGRQARK SACKCPRKGP NPGPWTRAAA WWGRLEGAKA SAKGEQVRDP GGHLWEQGHV
   241  SPCARFNQGH SCGSPKVSHT TWVS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00482 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00482 as an antibody target. Whether an autoantibody or antibody against LINC00482 could matter depends on whether native LINC00482 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00482 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00482 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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