Seroatlas · Human Serome Atlas

LINC00477

Putative transmembrane protein encoded by LINC00477

Also known as: CL067_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96M19
Gene: LINC00477
Canonical length: 166 aa

OverviewNCBI Gene

No narrative summary is available for LINC00477 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

166 residues, UniProt reviewed canonical sequence.

>Q96M19|LINC00477
     1  MLPFFSNTTS KSVSVSSFQG SPATPLSFLF FFFLCRAGSS MTGCFTFFLD FIFFFAGVLG
    61  PSPMGMYSGA STLTGFFLLR FLGQLSMDLE GLEWLGRASP SWWIFFSSSP SHRVPWGSCA
   121  SASAPRLPVP HPPSPLSKCP QHPRPRRTKG PGLRKLWGPG PPFFPS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00477 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 3
Mean surface accessibility (rSASA): 0.61

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00477 as an antibody target. Whether an autoantibody or antibody against LINC00477 could matter depends on whether native LINC00477 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00477 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00477 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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