Seroatlas · Human Serome Atlas

LINC00052

Putative uncharacterized protein encoded by LINC00052

Also known as: TMM83_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96N35
Gene: LINC00052
Canonical length: 136 aa

OverviewNCBI Gene

No narrative summary is available for LINC00052 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

136 residues, UniProt reviewed canonical sequence.

>Q96N35|LINC00052
     1  MNCDALLHHS AIPEDFLHIF LLLQKISVSL PLSLSQSVCL FYSISLCVSL LLHISLCVSV
    61  YVSLSLSSFP CFSLTHTHTH SQLSKDTSVL TFTFCFKQHT HFTLNYTSHA HELSAPSVHP
   121  TCVFTFKAAP SPRPAT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC00052 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.51

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC00052 as an antibody target. Whether an autoantibody or antibody against LINC00052 could matter depends on whether native LINC00052 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC00052 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC00052 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...