Seroatlas · Human Serome Atlas

LINC-PINT

Transcriptional regulator PINT87aa

Also known as: PNT87_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A455ZAR2
Gene: LINC-PINT
Canonical length: 87 aa

OverviewNCBI Gene

No narrative summary is available for LINC-PINT in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

87 residues, UniProt reviewed canonical sequence.

>A0A455ZAR2|LINC-PINT
     1  MLWLPDRGSC SARSPSGMLR GAPGGWRYGR RCGRRRQSCC CCCCCSHVGA PLSFHREASL
    61  VSHDGHDIMK QHCGEESIRG AHGYKNK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against LINC-PINT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.62

OntologyGO

Biological processes

negative regulation of transcription by RNA polymerase II

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

Transcriptional regulator PINT87aa
Transcriptional regulator PINT87aa

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads LINC-PINT as an antibody target. Whether an autoantibody or antibody against LINC-PINT could matter depends on whether native LINC-PINT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

LINC-PINT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label LINC-PINT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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