Seroatlas · Human Serome Atlas

KIF25-AS1

Putative uncharacterized protein KIF25-AS1

Also known as: KIAS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9Y6Z4
Gene: KIF25-AS1
Canonical length: 181 aa

OverviewNCBI Gene

No narrative summary is available for KIF25-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

181 residues, UniProt reviewed canonical sequence.

>Q9Y6Z4|KIF25-AS1
     1  MGDIFKNNGV LQGRLRAVAC APHCFGPRLR CLHHDQGLTE LAWGTWPHSH PVRHQPQMPS
    61  ARECCSIVCM AAKEVSAPKA PGSPWMVPGD VAMSGHRVGA LDERGHPNPQ TGHCRGGSVS
   121  VTWSSVSCCR GRLAAVRVMI ARDPSTCHLA KGCSPAWGFL PQARGPAGTR TPQRRCSSHE
   181  A

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against KIF25-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.67

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads KIF25-AS1 as an antibody target. Whether an autoantibody or antibody against KIF25-AS1 could matter depends on whether native KIF25-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

KIF25-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label KIF25-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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