Seroatlas · Human Serome Atlas

KANTR

KANTR integral membrane protein

Also known as: KANTR_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A0A1W2PQU2
Gene
KANTR
Canonical length
76 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

No narrative summary is available for KANTR in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

76 residues, UniProt reviewed canonical sequence.

>A0A1W2PQU2|KANTR
     1  MSPFSLLILV ICAFSLFFLI NLTRGLSILL VFSKNQLLAL LLLSIVSLFS ISLISALIFF
    61  DLLPSTFFGF ILLFFF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against KANTR can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
1
Mean surface accessibility (rSASA)
0.45
Highest tissue expression
4.7 nTPM

Expression across tissuesHPA

Tissue

  • cerebellum: 4.7 nTPM
  • hypothalamus: 3.8 nTPM
  • cerebral cortex: 2.3 nTPM
  • basal ganglia: 2.1 nTPM
  • amygdala: 1.8 nTPM
  • hippocampal formation: 1.7 nTPM

Single-cell type

  • somatotrophs: 243 nCPM
  • thyrotrophs: 209 nCPM
  • myonuclei: 197 nCPM
  • lactotrophs: 191 nCPM
  • sertoli cells: 171 nCPM
  • astrocytes: 161 nCPM

Immune cell

  • eosinophil: 0.2 nTPM
  • non-classical monocyte: 0.1 nTPM
  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM

Brain region

  • hypothalamus: 9.3 nTPM
  • cerebellum: 7.7 nTPM
  • midbrain: 7.4 nTPM
  • basal ganglia: 7.1 nTPM
  • cerebral cortex: 7.1 nTPM
  • pons: 6.1 nTPM

OntologyGO

Cellular components

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads KANTR as an antibody target. Whether an autoantibody or antibody against KANTR could matter depends on whether native KANTR is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

KANTR is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label KANTR as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/KANTR. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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