IGLV5-39
Immunoglobulin lambda variable 5-39
Also known as: LV539_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- A0A0G2JS06
- Gene
- IGLV5-39
- Canonical length
- 123 aa
OverviewNCBI Gene
No narrative summary is available for IGLV5-39 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
123 residues, UniProt reviewed canonical sequence.
>A0A0G2JS06|IGLV5-39
1 MAWTPLLLLL LSHCTGSLSQ PVLTQPTSLS ASPGASARFT CTLRSGINVG TYRIYWYQQK
61 PGSLPRYLLR YKSDSDKQQG SGVPSRFSGS KDASTNAGLL LISGLQSEDE ADYYCAIWYS
121 STSLocalizationUniProt · AlphaFold · HPA
Whether an antibody against IGLV5-39 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Cell surface
- Secreted
- No
- Transmembrane segments
- 0
OntologyGO
Biological processes
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads IGLV5-39 as an antibody target. Whether an autoantibody or antibody against IGLV5-39 could matter depends on whether native IGLV5-39 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
IGLV5-39 is annotated at the cell surface, where native IGLV5-39 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.
Annotation status
The present source text does not explicitly label IGLV5-39 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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