Seroatlas · Human Serome Atlas

IGLC6

Immunoglobulin lambda constant 6

Also known as: IGLC6_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0CF74
Gene: IGLC6
Canonical length: 106 aa

OverviewNCBI Gene

No narrative summary is available for IGLC6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

106 residues, UniProt reviewed canonical sequence.

>P0CF74|IGLC6
     1  GQPKAAPSVT LFPPSSEELQ ANKATLVCLI SDFYPGAVKV AWKADGSPVN TGVETTTPSK
    61  QSNNKYAASS YLSLTPEQWK SHRSYSCQVT HEGSTVEKTV APAECS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against IGLC6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0

OntologyGO

Biological processes

Molecular functions

antigen binding

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads IGLC6 as an antibody target. Whether an autoantibody or antibody against IGLC6 could matter depends on whether native IGLC6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

IGLC6 is annotated at the cell surface, where native IGLC6 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label IGLC6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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