Seroatlas · Human Serome Atlas

IGF2-AS

Putative insulin-like growth factor 2 antisense gene protein

Also known as: IG2AS_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6U949
Gene: IGF2-AS
Canonical length: 168 aa

OverviewNCBI Gene

No narrative summary is available for IGF2-AS in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

168 residues, UniProt reviewed canonical sequence.

>Q6U949|IGF2-AS
     1  MSKRKWRGFR GAQQERAQPP AASPQPCPAP HAGLPGGSRR RAPAPAGQQQ MRAESRSGAQ
    61  RRRGSARRGA HREAGGCVRG RTRSSGSERS NALWQAVDAA EALALSSPLR RPWDQAQHFT
   121  NPAPFSKGPQ SAPPSPPAGR RRRGADLALT PLAGEGHTRW RQPGRPGK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against IGF2-AS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.72

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads IGF2-AS as an antibody target. Whether an autoantibody or antibody against IGF2-AS could matter depends on whether native IGF2-AS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

IGF2-AS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label IGF2-AS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...