ID2B
Putative DNA-binding protein inhibitor ID-2B
Also known as: ID2B_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for ID2B in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
36 residues, UniProt reviewed canonical sequence.
>Q14602|ID2B
1 MKAFSPVRSI RKNSLLDHRL GISQSKTPVD DLMSLLLocalizationUniProt · AlphaFold · HPA
Whether an antibody against ID2B can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.67
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads ID2B as an antibody target. Whether an autoantibody or antibody against ID2B could matter depends on whether native ID2B is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
ID2B is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label ID2B as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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