Seroatlas · Human Serome Atlas

HSD52

Putative uncharacterized protein HSD52

Also known as: YA037_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q0P140
Gene: HSD52
Canonical length: 79 aa

OverviewNCBI Gene

No narrative summary is available for HSD52 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

79 residues, UniProt reviewed canonical sequence.

>Q0P140|HSD52
     1  MQDVHTKSIA CDGDLLPVLQ ENSISFQMLS LEMSGSFHSS PALENATITI LHVSLLSFFR
    61  GIQAPCRGSP LLVTDSPGG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against HSD52 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads HSD52 as an antibody target. Whether an autoantibody or antibody against HSD52 could matter depends on whether native HSD52 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

HSD52 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label HSD52 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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