Seroatlas · Human Serome Atlas

GTSCR1

Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein

Also known as: GTSC1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q86UQ5
Gene: GTSCR1
Canonical length: 136 aa

OverviewNCBI Gene

No narrative summary is available for GTSCR1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

136 residues, UniProt reviewed canonical sequence.

>Q86UQ5|GTSCR1
     1  MQSDIYHPGH SFPSWVLCWV HSCGHEGHLR ETAEIRKTHQ NGDLQIRGGR GRRESTEIFQ
    61  VASVTEGEES PPAICMEVFL FLWFIAPIYA CVCRIFKIQV RNTVKNSSTA SLAPSISTSE
   121  ERQIRIERHH YHLYGQ

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GTSCR1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.61

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GTSCR1 as an antibody target. Whether an autoantibody or antibody against GTSCR1 could matter depends on whether native GTSCR1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GTSCR1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label GTSCR1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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