Seroatlas · Human Serome Atlas

GSN-AS1

Putative uncharacterized protein GSN-AS1

Also known as: GSAS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9NRJ2
Gene: GSN-AS1
Canonical length: 163 aa

OverviewNCBI Gene

No narrative summary is available for GSN-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

163 residues, UniProt reviewed canonical sequence.

>Q9NRJ2|GSN-AS1
     1  MTHPLPHDSH TSGAPPLVNK SRDLANGPPF FSPLQSLWEE FLHLLFMGTL LFYRIATKAL
    61  RGKATLLKSH SKQPAQPGWE PGIRAPSPVP ASSLQDHSRL TSLSRTGKEQ RRTLSLIRKT
   121  SGTPTESTVA TAAASTTEVP SRLPWAARAG FKRTTGVCIA LPT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GSN-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.68

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GSN-AS1 as an antibody target. Whether an autoantibody or antibody against GSN-AS1 could matter depends on whether native GSN-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GSN-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label GSN-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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