Seroatlas · Human Serome Atlas

GPR32P1

Putative G-protein coupled receptor GPR32P1

Also known as: G32P1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NGA4
Gene: GPR32P1
Canonical length: 272 aa

OverviewNCBI Gene

No narrative summary is available for GPR32P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

272 residues, UniProt reviewed canonical sequence.

>Q8NGA4|GPR32P1
     1  MNGVSEGTRG CSDRQPGALT QGHSCSRKMN ASRCLSEEVG SLRPLTMAVL SASFVVGVLG
    61  NGLVPWVTVF RMARTVSTVC FFHLALADFM LSLSLPILVY YIVSRQWLLG EWACKLYTGF
   121  VFLTFSTSNC LLVLISVDRC ISVLYPVWAL NHRTEQRASW LAFGVWLLAA ALCSAHLKFR
   181  TTRKWNGCMQ CYLQFNLENE TAQMWTQEVF GRQMAVIMAH FLLGFLGPLA IIGTCAHLIR
   241  AKLLREGWVH ANRPKRLLLV LVSALSAGSH LT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GPR32P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 5
Mean surface accessibility (rSASA): 0.39

OntologyGO

Biological processes

Molecular functions

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GPR32P1 as an antibody target. Whether an autoantibody or antibody against GPR32P1 could matter depends on whether native GPR32P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GPR32P1 is annotated at the cell surface, where native GPR32P1 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label GPR32P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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