Seroatlas · Human Serome Atlas

GOLGA8DP

Putative golgin subfamily A member 8D

Also known as: GOG8D_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q0D2H9
Gene: GOLGA8DP
Canonical length: 430 aa

OverviewNCBI Gene

No narrative summary is available for GOLGA8DP in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

430 residues, UniProt reviewed canonical sequence.

>Q0D2H9|GOLGA8DP
     1  MEWKLEQSMR EQALLKAQLT QLKESLKEVQ LERDEYAEHL KGERARWQQR MRKMSQEVCS
    61  LKKEKKHDKY RVEKLERSLS KLKNQMAEPL PPEPPAVPSE VELQHLRKEL ERVAGALQAQ
   121  VEYNQRISLL NEGQKERLRE QEERLQEQQE RLPEQEERLQ QLAEPQNSFK ELNNENKSVL
   181  QLEQQVKELQ EKLGKERLEA ASQQKQQLTA QLSLMALPGE GHGGEHLDSE GEEAPRPMPS
   241  VPEDLESREA MSGFMDHLEE KADLSELVEK EELGFFQYYR ERCHQKVYHP ITKPGGSAKD
   301  AAPGGGHHQA GPGQGGDEGE AAGAAGDGVA AGGDYKGHSK FLVTAQNPAH EPSPGAPAPQ
   361  ELGAAHKHGD LCEVSLTDSV EPVQGEAREG SPHDNPTAQP IVQDHQEHPG LGSNCCVPFF
   421  CWAWLPRRRR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GOLGA8DP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Other membrane
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Golgi organization

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Coiled coil

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GOLGA8DP as an antibody target. Whether an autoantibody or antibody against GOLGA8DP could matter depends on whether native GOLGA8DP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GOLGA8DP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label GOLGA8DP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...