Seroatlas · Human Serome Atlas

GOLGA6L7

Golgin subfamily A member 6-like protein 7

Also known as: GG6L7_HUMAN, GOLGA6L7P

Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A0A1B0GV03
Gene
GOLGA6L7
Ensembl
ENSG00000261649
Chromosome
15
Canonical length
622 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

Predicted to be located in cis-Golgi network. [provided by Alliance of Genome Resources, Jul 2025]

Canonical amino-acid sequenceUniProt

622 residues, UniProt reviewed canonical sequence.

>A0A1B0GV03|GOLGA6L7
     1  MMSEKTQQRK LAGTKKKFTD YHQWNSAGVG TGATDTKKKK INHGANPETT TSGGCHSPED
    61  KQQNRAQLKE ENKASHQHQQ ALRRQLEAQD HTIRILMCQK TELETALHDS QDAARKFEED
   121  SKDLAARLHH SWHFAGELQR ALSAMSAEHE RADKYIKELT KEREAMSLEL FRNIITNKEL
   181  KEKNAELQEK LRLVETEKSE IQLHIKELKR KLETDKIPLP QVQTNTLQEK MWRQEEELRD
   241  QEELRDQEKL RKHEEKMWRQ EQRLRDQEKE LREQEQQMQE QEEQMRKQEE QMRKQEEQMR
   301  KQEEQMRKQE EQMRKQEEQM RKQEEQMGKQ EEQMGEQEEQ MRKQEKQMLK QKEQMRKQEE
   361  QMWKQEEQIG EQEEQMRKQE EQMWKQEEQI GEQEEQMRKQ EEQMWKQEEQ MGEQMRKQEE
   421  QMGEQEEQIR KQEEQMGEQE EQMRKQEEQM GEQEEQMRKQ EEQMGEQEEQ MRKQEEQMGE
   481  QEEQMGEQEE QMRKQVERLQ FKEERLWDEY EKMQEEEEKI RRQVEKRREK KERMGEQEKT
   541  QEERCSEPCL PPSKYPSDMS HPGSLEPARE AGKGYSHDNR TAQIMQLPPG MKNAQERPGL
   601  GSTSCIPFFY GGDKKKIKII SI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GOLGA6L7 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Intracellular
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.54
Highest tissue expression
26 nTPM

Expression across tissuesHPA

Tissue

  • testis: 26 nTPM
  • retina: 0.4 nTPM
  • adrenal gland: 0.2 nTPM
  • cerebral cortex: 0.2 nTPM
  • basal ganglia: 0.1 nTPM
  • bone marrow: 0.1 nTPM

Single-cell type

  • early spermatids: 175 nCPM
  • late primary spermatocytes: 160 nCPM
  • retinal horizontal cells: 12 nCPM
  • early primary spermatocytes: 11 nCPM
  • late spermatids: 8.9 nCPM
  • brain excitatory neurons: 7.9 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • pons: 9.2 nTPM
  • cerebellum: 9 nTPM
  • medulla oblongata: 8.2 nTPM
  • cerebral cortex: 7.7 nTPM
  • midbrain: 7.3 nTPM
  • basal ganglia: 7.2 nTPM

OntologyGO

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GOLGA6L7 as an antibody target. Whether an autoantibody or antibody against GOLGA6L7 could matter depends on whether native GOLGA6L7 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GOLGA6L7 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label GOLGA6L7 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/GOLGA6L7. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

© 2026 · Seroatlas, Discover Oregon LLC · Terms of use

Loading the interactive Seroatlas protein explorer...