Seroatlas · Human Serome Atlas

GOLGA6L24

Golgin subfamily A member 6-like protein 24

Also known as: GG6LX_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0DX00
Gene: GOLGA6L24
Canonical length: 832 aa
Protein class: Predicted intracellular proteins

OverviewNCBI Gene

No narrative summary is available for GOLGA6L24 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

832 residues, UniProt reviewed canonical sequence.

>P0DX00|GOLGA6L24
     1  MWPQPHLPTH PHLPTHPHLP THPHLPTHPH LPTHPMMSKE TRQSKLAEAK EQLTDHHPQT
    61  NPSVGTAASD TKKKKINNGT NPETTTSGGC HSPEDEQKAS HQHQEALRRE LEAQVQTIRI
   121  LTCQKTELQM ALYYSQHAVK QLEGEARDLI SRLHDSWKFA GELEQALSAV ATQKKKADRY
   181  IEELTKERDA LSLELYRNTI TDEELKEKNA KLQEKLQLVE SEKSEIQLNV KELKRKLERA
   241  KLLLPQQQLQ AEADHLGKEL QSVSAKLQAQ VEENELWNRL NQQQEEKMWR QEEKIQEREE
   301  KIQEQEEKIR EQEEKMRRQE EMMWEKEEKM RRQEEMMWEK EEKIRELEEK MHEQEKIREQ
   361  EEKRQEEEKI REQEKRQEQE AKMWRQEEKI REQEEKIREQ EKKMWRQEEK IHEQEKIREE
   421  EKRQEQEEMW RQEEKIREQE EIWRQKEKMH EQEEKIRKQE EKVWRQEEKM HDQEEKIREQ
   481  EEKVWRQEEK IREQEEKMWR QEEKIREQEE MWREEEKMHE QEKIWEEEKR QEQEDKMWRQ
   541  EEKIREQEEK VWRQEEKIRE QEEKRQEQEE KMWKQEEKIR EQEEKTREQE KIREQEEKIR
   601  EQEEMMQEQE EKMGEQEEKM QEQEKMRRQE EKIREQEEKI REQKEKIREQ EEKIWEQEEK
   661  IREQEEMMQE QEEKMGEQEE KMWEQEEEMQ EQEEKMRRQE EKIREQEKKI REQEEKIREQ
   721  EEMMQEQEEK MGEQEGKMCE QEAKMQEQEE KMRRQEEKIR EQEKKIREQE EKIREQEEMM
   781  QEQEEKMWEQ EEKMCEQEEK MQEQEEKMRR QEEKMREQEV RLRQQEEKMQ EH

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GOLGA6L24 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.51
Highest tissue expression: 0.8 nTPM

Expression across tissuesHPA

Tissue

testis: 0.8 nTPM
adipose tissue: 0 nTPM
adrenal gland: 0 nTPM
appendix: 0 nTPM
bone marrow: 0 nTPM
breast: 0 nTPM

Single-cell type

early spermatids: 12 nCPM
late primary spermatocytes: 4.4 nCPM
late spermatids: 3.4 nCPM
differentiating spermatogonia: 0.1 nCPM
undifferentiated spermatogonia: 0.1 nCPM
adipocytes: 0 nCPM

Immune cell

basophil: 0 nTPM
classical monocyte: 0 nTPM
eosinophil: 0 nTPM
gdT-cell: 0 nTPM
intermediate monocyte: 0 nTPM
MAIT T-cell: 0 nTPM

Brain region

white matter: 0.2 nTPM
cerebral cortex: 0.1 nTPM
amygdala: 0 nTPM
basal ganglia: 0 nTPM
cerebellum: 0 nTPM
choroid plexus: 0 nTPM

Protein domainsUniProt · Pfam · InterPro

Golgin subfamily A member 6-like

KeywordsUniProt

Coiled coil

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GOLGA6L24 as an antibody target. Whether an autoantibody or antibody against GOLGA6L24 could matter depends on whether native GOLGA6L24 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GOLGA6L24 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label GOLGA6L24 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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