GOLGA2P5
Putative golgin subfamily A member 2B
Also known as: GGA2B_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for GOLGA2P5 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
144 residues, UniProt reviewed canonical sequence.
>Q9HBQ8|GOLGA2P5
1 MDSEEEEEVP QPMPSIPEDL ESQKAMVAFF NSAVASAEEE QARLCGQLKE CTASAWLICW
61 PRPRRNLRQQ PQPQELGVIP CVGRPTRPCR GPWRSCGRVH RTVPEPEGSA EGGGVHQQAG
121 PGQGRGEGEA AGAGVACGRL QQVALocalizationUniProt · AlphaFold · HPA
Whether an antibody against GOLGA2P5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.65
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads GOLGA2P5 as an antibody target. Whether an autoantibody or antibody against GOLGA2P5 could matter depends on whether native GOLGA2P5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
GOLGA2P5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label GOLGA2P5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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