Seroatlas · Human Serome Atlas

GKN3P

Gastrokine-3

Also known as: GKN3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0CG01
Gene: GKN3P
Canonical length: 181 aa

OverviewNCBI Gene

No narrative summary is available for GKN3P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

181 residues, UniProt reviewed canonical sequence.

>P0CG01|GKN3P
     1  MKHLVASSIL GVFVLTPSLA MMNIRFNHPL YGSFGTQIIH IGAFQGMVSI RDNNIFSEWD
    61  GILDYKNALL VAKVFNKMAC VLARMDKAVF PSLDDISKAL DKQAFKYYPS TRGLTYTVLP
   121  SWVKNLAQYG KPIKNMCRDD PTYFAQQQKE GTALAIDSNS CFEIQLLSFM GLFICGETPG
   181  L

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against GKN3P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.35

OntologyGO

Biological processes

regulation of cell population proliferation

Cellular components

extracellular space

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads GKN3P as an antibody target. Whether an autoantibody or antibody against GKN3P could matter depends on whether native GKN3P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

GKN3P is annotated as secreted, so native GKN3P circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label GKN3P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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