GAGE5
G antigen 5
Also known as: GAGE5_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for GAGE5 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
117 residues, UniProt reviewed canonical sequence.
>Q13069|GAGE5
1 MSWRGRSTYY WPRPRRYVQP PEVIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE
61 DEGASAGQGP KPEADSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEKQSQCLocalizationUniProt · AlphaFold · HPA
Whether an antibody against GAGE5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.71
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads GAGE5 as an antibody target. Whether an autoantibody or antibody against GAGE5 could matter depends on whether native GAGE5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
GAGE5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label GAGE5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
Loading the interactive Seroatlas protein explorer...