Seroatlas · Human Serome Atlas

FTH1P19

Putative ferritin heavy polypeptide-like 19

Also known as: FHL19_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C7X4
Gene: FTH1P19
Canonical length: 201 aa

OverviewNCBI Gene

No narrative summary is available for FTH1P19 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

201 residues, UniProt reviewed canonical sequence.

>P0C7X4|FTH1P19
     1  MAFYFDQDDA ALEHFDRYFL RQSQEKREHA QELMSLQNLR GGRICLHDIR KPEGQGWESG
    61  LKAMECTFHL EKNINQSLLE LHQLARENGD PQLCDFLEND FLNQQAKTIK ELGGYLSNLH
   121  KMGAPEAGLA EYLFNKLTLG RSQKHTRAQT GPTATGCLPL LAPPGGTSMF PFQNILFIFL
   181  LSVLPLLAIK LSVLKAIKVS S

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FTH1P19 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.38

OntologyGO

Biological processes

Molecular functions

Cellular components

cytoplasm

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FTH1P19 as an antibody target. Whether an autoantibody or antibody against FTH1P19 could matter depends on whether native FTH1P19 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FTH1P19 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FTH1P19 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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